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ULK3 抗体 (AA 44-240)

ULK3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169213
发货至: 中国
  • 抗原 See all ULK3 抗体
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    抗原表位
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-240
    适用
    • 54
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 61
    • 7
    • 2
    克隆类型
    • 64
    • 6
    多克隆
    标记
    • 31
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK3 antibody is un-conjugated
    应用范围
    • 62
    • 39
    • 10
    • 10
    • 9
    • 6
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Serine/threonine-protein kinase ULK3 protein (44-240AA)
    亚型
    IgG
    Top Product
    Discover our top product ULK3 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    别名
    ULK3 (ULK3 产品)
    别名
    zgc:162196 antibody, 1200015E14Rik antibody, unc-51 like kinase 3 antibody, unc-51 like kinase 3 L homeolog antibody, unc-51-like kinase 3 antibody, ULK3 antibody, ulk3 antibody, Ulk3 antibody, ulk3.L antibody
    背景

    Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

    Aliases: DKFZP434C131 antibody, FLJ90566 antibody, Serine/threonine-protein kinase ULK3 antibody, Ulk3 antibody, ULK3_HUMAN antibody, unc 51 like kinase 3 (C. elegans) antibody, Unc-51-like kinase 3 antibody

    UniProt
    Q6PHR2
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