TAO Kinase 1 (TAOK1) (AA 400-659) 抗体
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- 抗原 See all TAO Kinase 1 (TAOK1) 抗体
- TAO Kinase 1 (TAOK1)
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抗原表位
- AA 400-659
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Serine/threonine-protein kinase TAO1 protein (400-659AA)
- 亚型
- IgG
- Top Product
- Discover our top product TAOK1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TAO Kinase 1 (TAOK1)
- 别名
- TAOK1 (TAOK1 产品)
- 别名
- TAOK1 antibody, LOC733788 antibody, KFC-B antibody, MAP3K16 antibody, MARKK antibody, PSK-2 antibody, PSK2 antibody, TAO1 antibody, hKFC-B antibody, hTAOK1 antibody, 2810468K05Rik antibody, AU020252 antibody, D130018F14Rik antibody, Map3k16 antibody, Markk antibody, Psk2 antibody, mKIAA1361 antibody, taok1-b antibody, microRNA 4523 antibody, TAO kinase 1 antibody, serine/threonine-protein kinase TAO1 antibody, TAO kinase 1 S homeolog antibody, MIR4523 antibody, TAOK1 antibody, taok1 antibody, LOC100399784 antibody, Taok1 antibody, taok1.S antibody
- 背景
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Background: Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating \'Thr-208\' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade.
Aliases: 2810468K05Rik antibody, AU020252 antibody, D130018F14Rik antibody, EC 2.7.11.1 antibody, FLJ14314 antibody, hKFC B antibody, hKFC-B antibody, KIAA1361 antibody, Kinase from chicken homolog B antibody, MAP3K16 antibody, MARK kinase antibody, MARKK antibody, MGC29021 antibody, Microtubule affinity regulating kinase kinase antibody, mKIAA1361 antibody, Prostate-derived sterile 20-like kinase 2 antibody, PSK2 antibody, Serine/threonine kinase TAO1 antibody, Serine/threonine protein kinase TAO1 antibody, Serine/threonine protein kinase TAO1 homolog antibody, Serine/threonine-protein kinase TAO1 antibody, STE20 like kinase antibody, STE20 like kinase PSK2 antibody, STE20-like kinase PSK2 antibody, TAO kinase 1 antibody, Taok1 antibody, TAOK1_HUMAN antibody, Thousand and one amino acid protein 1 antibody
- UniProt
- Q7L7X3
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