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PKN2 抗体 (AA 925-969)

PKN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169080
发货至: 中国
  • 抗原 See all PKN2 抗体
    PKN2 (Protein Kinase N2 (PKN2))
    抗原表位
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 925-969
    适用
    • 30
    • 10
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 35
    • 2
    克隆类型
    • 34
    • 3
    多克隆
    标记
    • 24
    • 8
    • 4
    • 1
    This PKN2 antibody is un-conjugated
    应用范围
    • 32
    • 11
    • 10
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine/threonine-protein kinase N2 protein (925-969AA)
    亚型
    IgG
    Top Product
    Discover our top product PKN2 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PKN2 (Protein Kinase N2 (PKN2))
    别名
    PKN2 (PKN2 产品)
    别名
    PAK2 antibody, PRK2 antibody, PRKCL2 antibody, PRO2042 antibody, Pak-2 antibody, 6030436C20Rik antibody, AI507382 antibody, Prkcl2 antibody, Stk7 antibody, pak2 antibody, prk2 antibody, pak-2 antibody, pro2042 antibody, PKN2 antibody, si:ch211-83f14.1 antibody, wu:fa97c07 antibody, protein kinase N2 antibody, protein kinase N2 L homeolog antibody, PKN2 antibody, Pkn2 antibody, pkn2.L antibody, pkn2 antibody
    背景

    Background: PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Phosphorylates HCV NS5B leading to stimulation of HCV RNA replication.

    Aliases: Cardiolipin activated protein kinase Pak2 antibody, MGC150606 antibody, MGC71074 antibody, PAK 2 antibody, PAK2 antibody, PKN gamma antibody, PKN2 antibody, PKN2_HUMAN antibody, PRK2 antibody, PRKCL2 antibody, PRO2042 antibody, Protein kinase C like 2 antibody, Protein kinase C related kinase 2 antibody, Protein kinase C-like 2 antibody, Protein kinase N2 antibody, Protein-kinase C-related kinase 2 antibody, Serine/threonine-protein kinase N2 antibody

    UniProt
    Q16513
    途径
    Cell-Cell Junction Organization
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