SRSF1 抗体 (AA 1-248)
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- 抗原 See all SRSF1 抗体
- SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))
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抗原表位
- AA 1-248
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRSF1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Serine/arginine-rich splicing factor 1 protein (1-248AA)
- 亚型
- IgG
- Top Product
- Discover our top product SRSF1 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))
- 别名
- SRSF1 (SRSF1 产品)
- 别名
- ASF antibody, SF2 antibody, SF2p33 antibody, SFRS1 antibody, SRp30a antibody, 1110054N12Rik antibody, 5730507C05Rik antibody, 6330415C05Rik antibody, AI482334 antibody, AW491331 antibody, Asf antibody, Sf2 antibody, Sfrs1 antibody, DKFZp469K2419 antibody, sfrs1 antibody, sfrs1b antibody, wu:fb80g05 antibody, zgc:111894 antibody, zgc:65898 antibody, zgc:76897 antibody, asf antibody, sf2 antibody, sf2p33 antibody, srp30a antibody, sfrs1a antibody, sfrs1l antibody, wu:fb52g10 antibody, wu:fb97g12 antibody, zgc:66146 antibody, serine and arginine rich splicing factor 1 antibody, serine/arginine-rich splicing factor 1 antibody, serine/arginine-rich splicing factor 1b antibody, serine/arginine-rich splicing factor 1 L homeolog antibody, serine/arginine-rich splicing factor 1a antibody, SRSF1 antibody, Srsf1 antibody, srsf1b antibody, srsf1.L antibody, srsf1a antibody
- 背景
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Background: Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5\\\'- and 3\\\'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5\\\'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5\\\'-RGAAGAAC-3\\\' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5\\\'-CGAGGCG-3\\\' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway.
Aliases: Alternative splicing factor 1 antibody, Alternative-splicing factor 1 antibody, arginine/serine-rich 1 antibody, ASF 1 antibody, ASF antibody, ASF-1 antibody, ASF1 antibody, FLJ53078 antibody, MGC5228 antibody, P33 subunit antibody, Pre mRNA splicing factor SF2 P33 subunit antibody, pre-mRNA-splicing factor SF2 antibody, Serine/arginine-rich splicing factor 1 antibody, SF2 antibody, SF2P33 antibody, SFRS1 antibody, Splicing factor 2 alternate splicing factor antibody, Splicing factor 2 antibody, Splicing factor antibody, Splicing factor arginine/serine rich 1 antibody, SR Splicing factor 1 antibody, SRp30a antibody, srsf1 antibody, SRSF1_HUMAN antibody
- UniProt
- Q07955
- 途径
- Ribonucleoprotein Complex Subunit Organization
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