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Seryl-tRNA Synthetase (SARS) (AA 2-233) 抗体

SARS 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7168949
发货至: 中国
  • 抗原 See all Seryl-tRNA Synthetase (SARS) 抗体
    Seryl-tRNA Synthetase (SARS)
    抗原表位
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    AA 2-233
    适用
    • 27
    • 14
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 25
    • 2
    克隆类型
    • 26
    • 1
    多克隆
    标记
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 17
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Serine--tRNA ligase, cytoplasmic protein (2-233AA)
    亚型
    IgG
    Top Product
    Discover our top product SARS Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Seryl-tRNA Synthetase (SARS)
    别名
    SARS (SARS 产品)
    别名
    SERRS antibody, SERS antibody, Sars1 antibody, Strs antibody, serRS antibody, SerRS antibody, wu:fk51f08 antibody, zgc:92152 antibody, seryl-tRNA synthetase antibody, seryl-aminoacyl-tRNA synthetase antibody, SARS antibody, Sars antibody, sars antibody
    背景

    Background: Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at \\\'Lys-16\\\' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA (PubMed:19423848, PubMed:19423847, PubMed:24940000).

    Aliases: C78314 antibody, cytoplasmic antibody, EC 6.1.1.11 antibody, FLJ36399 antibody, sarS antibody, Sars1 antibody, Serine tRNA ligase 1, cytoplasmic antibody, Serine tRNA ligase antibody, Serine--tRNA ligase antibody, serine--tRNA ligase, cytoplasmic antibody, SerRS antibody, SERS antibody, Seryl tRNA Ser/Sec synthetase antibody, Seryl tRNA synthetase antibody, Seryl tRNA synthetase cytoplasmic antibody, Seryl-tRNA Ser/Sec synthetase antibody, Seryl-tRNA synthetase antibody, seryl-tRNA synthetase, cytoplasmic antibody, Seryl-tRNA(Ser/Sec) synthetase antibody, Strs antibody, SYSC_HUMAN antibody

    UniProt
    P49591
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