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- 抗原 See all HTRA1 抗体
- HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
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抗原表位
- AA 23-248
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HTRA1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Serine protease HTRA1 protein (23-248AA)
- 亚型
- IgG
- Top Product
- Discover our top product HTRA1 Primary Antibody
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anti-HtrA Serine Peptidase 1 (HTRA1) (AA 116-147), (N-Term) antibody
HTRA1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB02326 unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) antibodyHTRA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 381-412), (C-Term) antibodyHTRA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB02327 unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 122-171) antibodyHTRA1 适用: 人, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 22-160) antibodyHTRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (N-Term) antibodyHTRA1 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-HtrA Serine Peptidase 1 (HTRA1) (AA 389-419), (C-Term) antibodyHTRA1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
- 别名
- HTRA1 (HTRA1 产品)
- 背景
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Background: Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.
Aliases: ARMD7 antibody, CARASIL antibody, High-temperature requirement A serine peptidase 1 antibody, HtrA antibody, HtrA serine peptidase 1 antibody, HTRA1 antibody, HTRA1_HUMAN antibody, IGFBP5 protease antibody, L56 antibody, ORF480 antibody, Protease serine 11 (IGF binding) antibody, protease serine 11 antibody, PRSS11 antibody, Serine protease 11 antibody, Serine protease HTRA1 antibody, Serine protease HTRA1 precursor antibody
- UniProt
- Q92743
- 途径
- Growth Factor Binding
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