SFRP1 抗体 (AA 170-240)
-
- 抗原 See all SFRP1 抗体
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
-
抗原表位
- AA 170-240
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SFRP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Secreted frizzled-related protein 1 protein (170-240AA)
- 亚型
- IgG
- Top Product
- Discover our top product SFRP1 Primary Antibody
-
-
- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:50-1:500,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
- 别名
- SFRP1 (SFRP1 产品)
- 背景
-
Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Aliases: Frizzled related protein 1 antibody, FRP 1 antibody, FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP-2 antibody, SARP2 antibody, Secreted apoptosis related protein 2 antibody, Secreted apoptosis-related protein 2 antibody, Secreted frizzled related protein 1 antibody, Secreted frizzled related protein antibody, Secreted frizzled-related protein 1 antibody, SFRP 1 antibody, sFRP-1 antibody, SFRP1 antibody, SFRP1_HUMAN antibody
- UniProt
- Q8N474
- 途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
-