SLFN11 抗体 (AA 670-821)
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- 抗原 See all SLFN11 products
- SLFN11 (Schlafen Family Member 11 (SLFN11))
- 抗原表位
- AA 670-821
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLFN11 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Schlafen family member 11 protein (670-821AA)
- 亚型
- IgG
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anti-Schlafen Family Member 11 (SLFN11) antibody
SLFN11 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:500, IF:1:50-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SLFN11 (Schlafen Family Member 11 (SLFN11))
- 别名
- SLFN11 (SLFN11 产品)
- 别名
- SLFN8/9 antibody, schlafen family member 11 antibody, SLFN11 antibody, LOC100071612 antibody
- 背景
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Background: Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.
Aliases: SLFN11 antibody, Schlafen family member 11 antibody, EC 3.6.-.- antibody
- UniProt
- Q7Z7L1
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