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SKP2 抗体 (AA 1-424)

SKP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7168555
发货至: 中国
  • 抗原 See all SKP2 抗体
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    抗原表位
    • 16
    • 8
    • 7
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-424
    适用
    • 70
    • 36
    • 34
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 63
    • 8
    • 1
    克隆类型
    • 64
    • 7
    多克隆
    标记
    • 41
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SKP2 antibody is un-conjugated
    应用范围
    • 50
    • 19
    • 18
    • 18
    • 13
    • 13
    • 13
    • 12
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human S-phase kinase-associated protein 2 protein (1-424AA)
    亚型
    IgG
    Top Product
    Discover our top product SKP2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
    别名
    SKP2 (SKP2 产品)
    别名
    FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
    背景

    Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration.

    Aliases: CDK2/Cyclin A associated protein p45 antibody, Cyclin A/CDK2 associated protein p45 antibody, Cyclin-A/CDK2-associated protein p45 antibody, F box protein Skp2 antibody, F box/LRR repeat protein 1 antibody, F-box protein Skp2 antibody, F-box/LRR-repeat protein 1 antibody, FBL 1 antibody, FBL1 antibody, FBXL 1 antibody, FBXL1 antibody, FLB 1 antibody, FLB1 antibody, MGC1366 antibody, p45 antibody, p45skp2 antibody, S phase kinase associated protein 2 (p45) antibody, S phase kinase associated protein 2 antibody, S-phase kinase-associated protein 2 antibody, S-phase kinase-associated protein 2 E3 ubiquitin protein ligase antibody, SKP 2 antibody, Skp2 antibody, SKP2_HUMAN antibody

    UniProt
    Q13309
    途径
    Mitotic G1-G1/S Phases
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