RBM4 抗体 (AA 121-205) (FITC)
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- 抗原 See all RBM4 抗体
- RBM4 (RNA Binding Motif Protein 4 (RBM4))
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抗原表位
- AA 121-205
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBM4 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human RNA-binding protein 4 protein (121-205AA)
- 亚型
- IgG
- Top Product
- Discover our top product RBM4 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RBM4 (RNA Binding Motif Protein 4 (RBM4))
- 别名
- RBM4 (RBM4 产品)
- 背景
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Background: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5\\\'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3\\\'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3\\\'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5\\\'-CGCGCG[GCA]-3\\\' motif in vitro.
Aliases: dkfzp547k0918 antibody, hLark antibody, lark antibody, Lark homolog antibody, lark homologue antibody, mgc75138 antibody, RBM4 antibody, rbm4 lark antibody, RBM4_HUMAN antibody, RNA binding motif 4 antibody, RNA binding motif 4a antibody, RNA-binding motif protein 4 antibody, RNA-binding motif protein 4a antibody, RNA-binding protein 4 antibody
- UniProt
- Q9BWF3
- 途径
- Regulation of Muscle Cell Differentiation, Photoperiodism
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