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RBM4 抗体 (AA 121-205)

RBM4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7168345
发货至: 中国
  • 抗原 See all RBM4 抗体
    RBM4 (RNA Binding Motif Protein 4 (RBM4))
    抗原表位
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-205
    适用
    • 23
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 22
    • 1
    克隆类型
    • 22
    • 1
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    This RBM4 antibody is un-conjugated
    应用范围
    • 19
    • 15
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human RNA-binding protein 4 protein (121-205AA)
    亚型
    IgG
    Top Product
    Discover our top product RBM4 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RBM4 (RNA Binding Motif Protein 4 (RBM4))
    别名
    RBM4 (RBM4 产品)
    背景

    Background: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5\\\'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3\\\'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3\\\'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5\\\'-CGCGCG[GCA]-3\\\' motif in vitro.

    Aliases: dkfzp547k0918 antibody, hLark antibody, lark antibody, Lark homolog antibody, lark homologue antibody, mgc75138 antibody, RBM4 antibody, rbm4 lark antibody, RBM4_HUMAN antibody, RNA binding motif 4 antibody, RNA binding motif 4a antibody, RNA-binding motif protein 4 antibody, RNA-binding motif protein 4a antibody, RNA-binding protein 4 antibody

    UniProt
    Q9BWF3
    途径
    Regulation of Muscle Cell Differentiation, Photoperiodism
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