RNF11 抗体 (AA 1-154)
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- 抗原 See all RNF11 抗体
- RNF11 (Ring Finger Protein 11 (RNF11))
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抗原表位
- AA 1-154
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF11 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human RING finger protein 11 protein (1-154AA)
- 亚型
- IgG
- Top Product
- Discover our top product RNF11 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RNF11 (Ring Finger Protein 11 (RNF11))
- 别名
- RNF11 (RNF11 产品)
- 别名
- SID1669 antibody, Sid1669 antibody, rnf11 antibody, rnf11-a antibody, zgc:114095 antibody, zgc:63861 antibody, ring finger protein 11 antibody, ring finger protein 11 L homeolog antibody, ring finger protein 11b antibody, ring finger protein 11a antibody, RNF11 antibody, Rnf11 antibody, rnf11.L antibody, rnf11b antibody, rnf11a antibody
- 背景
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Background: Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates \\\'Lys-63\\\' polyubiquitin chains on RIPK1 and catalyzes the formation of \\\'Lys-48\\\'-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.
Aliases: CGI 123 antibody, RING finger protein 11 antibody, RNF11 antibody, RNF11_HUMAN antibody, Sid 1669 antibody, SID1669 antibody
- UniProt
- Q9Y3C5
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