RRM2B 抗体 (AA 1-351)
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- 抗原 See all RRM2B 抗体
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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抗原表位
- AA 1-351
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RRM2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B protein (1-351AA)
- 亚型
- IgG
- Top Product
- Discover our top product RRM2B Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- 别名
- RRM2B (RRM2B 产品)
- 别名
- p53r2 antibody, RRM2B antibody, MTDPS8A antibody, MTDPS8B antibody, P53R2 antibody, p53R2 antibody, ribonucleotide reductase M2 B (TP53 inducible) S homeolog antibody, ribonucleotide reductase regulatory TP53 inducible subunit M2B antibody, ribonucleotide reductase M2 B (TP53 inducible) antibody, rrm2b.S antibody, RRM2B antibody, rrm2b antibody, Rrm2b antibody
- 背景
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Background: Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
Aliases: DKFZp686M05248 antibody, MGC102856 antibody, MGC42116 antibody, MTDPS8A antibody, MTDPS8B antibody, p53 inducible ribonucleotide reductase small subunit 2 homolog antibody, p53 inducible ribonucleotide reductase small subunit 2 like protein antibody, P53 inducible ribonucleotide reductase small subunit 2 short form beta antibody, p53 R2 antibody, p53-inducible ribonucleotide reductase small subunit 2-like protein antibody, p53R2 antibody, Ribonucleoside diphosphate reductase M2 subunit B antibody, Ribonucleoside-diphosphate reductase subunit M2 B antibody, Ribonucleotide reductase M2 B (TP53 inducible) antibody, Ribonucleotide reductase M2 B antibody, Ribonucleotide reductase small subunit like 2 p53 inducible antibody, RIR2B_HUMAN antibody, RRM 2B antibody, RRM2B antibody, TP53 inducible ribonucleotide reductase M2 B antibody, TP53-inducible ribonucleotide reductase M2 B antibody
- UniProt
- Q7LG56
- 途径
- p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
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