ARHGEF5 抗体 (AA 433-507)
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- 抗原 See all ARHGEF5 抗体
- ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
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抗原表位
- AA 433-507
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF5 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)
- 亚型
- IgG
- Top Product
- Discover our top product ARHGEF5 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))
- 别名
- ARHGEF5 (ARHGEF5 产品)
- 别名
- ARHGEF5 antibody, GEF5 antibody, P60 antibody, TIM antibody, TIM1 antibody, 2210412D05Rik antibody, AA717842 antibody, AW495314 antibody, Tim1 antibody, Rho guanine nucleotide exchange factor 5 antibody, rho guanine nucleotide exchange factor 5 antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, ARHGEF5 antibody, LOC100414419 antibody, Arhgef5 antibody
- 背景
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Background: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).
Aliases: ARHG5_HUMAN antibody, ARHGEF 5 antibody, ARHGEF5 antibody, DKFZp686N1969 antibody, ephexin 3 antibody, Ephexin-3 antibody, GEF 5 antibody, GEF5 antibody, Guanine nucleotide regulatory protein TIM antibody, Oncogene TIM antibody, P60 antibody, p60 TIM antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, Rho guanine nucleotide exchange factor 5 antibody, TIM 1 antibody, TIM antibody, TIM1 antibody, Transforming immortalized mammary oncogene antibody
- UniProt
- Q12774
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