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p130 抗体 (AA 417-616)

RBL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167791
发货至: 中国
  • 抗原 See all p130 (RBL2) 抗体
    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
    抗原表位
    • 15
    • 9
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    • 7
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
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    • 1
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    AA 417-616
    适用
    • 69
    • 28
    • 26
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 63
    • 7
    克隆类型
    • 64
    • 6
    多克隆
    标记
    • 29
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This p130 antibody is un-conjugated
    应用范围
    • 31
    • 27
    • 14
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
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    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Retinoblastoma-like protein 2 protein (417-616AA)
    亚型
    IgG
    Top Product
    Discover our top product RBL2 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
    别名
    RBL2 (RBL2 产品)
    别名
    RBL2 antibody, RBR2 antibody, RRB2a antibody, PRB2 antibody, RBR-2 antibody, Rb2 antibody, p130 antibody, P130 antibody, retinoblastoma-like 2 (p130) antibody, RB transcriptional corepressor like 2 antibody, related to retinoblastoma 2 antibody, RBL2 antibody, LOC541652 antibody, Rbl2 antibody
    背景

    Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 \'Lys-20\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.

    Aliases: 130 kDa retinoblastoma associated protein antibody, 130 kDa retinoblastoma-associated protein antibody, IB4 antibody, p130 antibody, PPAR-alpha-interacting complex protein 128 antibody, PRB2 antibody, Rb2 antibody, Rbl2 antibody, RBL2_HUMAN antibody, RBR 2 antibody, RBR-2 antibody, RBR2 antibody, Retinoblastoma like 2 antibody, Retinoblastoma-like protein 2 antibody, Retinoblastoma-related protein 2 antibody, RIC128 antibody

    UniProt
    Q08999
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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