p107 抗体 (AA 201-500) (HRP)
-
- 抗原 See all p107 (RBL1) 抗体
- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
-
抗原表位
- AA 201-500
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This p107 antibody is conjugated to HRP
-
应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)
- 亚型
- IgG
- Top Product
- Discover our top product RBL1 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
- 别名
- RBL1 (RBL1 产品)
- 别名
- p107 antibody, prb1 antibody, fj58e06 antibody, wu:fj58e06 antibody, CP107 antibody, PRB1 antibody, AW547426 antibody, retinoblastoma-like 1 L homeolog antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma-like 1 (p107) antibody, retinoblastoma-like 1 antibody, rbl1.L antibody, RBL1 antibody, rbl1 antibody, Rbl1 antibody
- 背景
-
Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 \'Lys-20\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Aliases: 107 kDa retinoblastoma-associated protein antibody, Cellular protein 107 antibody, Cellular protein p107 antibody, CP107 antibody, MGC40006 antibody, p107 antibody, PRB1 antibody, RBL1 antibody, RBL1_HUMAN antibody, Retinoblastoma like protein 1 antibody, retinoblastoma-like 1 (p107) antibody, Retinoblastoma-like protein 1 antibody
- UniProt
- P28749
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
-