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p107 抗体 (AA 201-500)

RBL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167787
发货至: 中国
  • 抗原 See all p107 (RBL1) 抗体
    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
    抗原表位
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    AA 201-500
    适用
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    宿主
    • 74
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    克隆类型
    • 75
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    多克隆
    标记
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    This p107 antibody is un-conjugated
    应用范围
    • 65
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)
    亚型
    IgG
    Top Product
    Discover our top product RBL1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:2000-1:5000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
    别名
    RBL1 (RBL1 产品)
    别名
    p107 antibody, prb1 antibody, fj58e06 antibody, wu:fj58e06 antibody, CP107 antibody, PRB1 antibody, AW547426 antibody, retinoblastoma-like 1 L homeolog antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma-like 1 (p107) antibody, retinoblastoma-like 1 antibody, rbl1.L antibody, RBL1 antibody, rbl1 antibody, Rbl1 antibody
    背景

    Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 \\\'Lys-20\\\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.

    Aliases: 107 kDa retinoblastoma-associated protein antibody, Cellular protein 107 antibody, Cellular protein p107 antibody, CP107 antibody, MGC40006 antibody, p107 antibody, PRB1 antibody, RBL1 antibody, RBL1_HUMAN antibody, Retinoblastoma like protein 1 antibody, retinoblastoma-like 1 (p107) antibody, Retinoblastoma-like protein 1 antibody

    UniProt
    P28749
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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