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CoREST 抗体 (AA 394-482) (HRP)

RCOR1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7167724
发货至: 中国
  • 抗原 See all CoREST (RCOR1) 抗体
    CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
    抗原表位
    • 9
    • 8
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    AA 394-482
    适用
    • 38
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 38
    • 1
    • 1
    克隆类型
    • 38
    • 2
    多克隆
    标记
    • 21
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CoREST antibody is conjugated to HRP
    应用范围
    • 28
    • 16
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human REST corepressor 1 protein (394-482AA)
    亚型
    IgG
    Top Product
    Discover our top product RCOR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
    别名
    RCOR1 (RCOR1 产品)
    别名
    COREST antibody, RCOR antibody, 5730409O11 antibody, 6720480E22Rik antibody, AU042633 antibody, D12Wsu95e antibody, mKIAA0071 antibody, rcor1 antibody, xcoREST antibody, RCOR1 antibody, im:6904264 antibody, si:dkey-46n18.7 antibody, zgc:158607 antibody, RGD1305743 antibody, REST corepressor 1 antibody, REST corepressor 1 L homeolog antibody, RCOR1 antibody, Rcor1 antibody, rcor1.L antibody, rcor1 antibody
    背景

    Background: Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.

    Aliases: COREST antibody, KIAA0071 antibody, Nr2b2 antibody, Nuclear receptor coregulator 1 antibody, Nuclear receptor subfamily 2 group B member 2 antibody, Protein CoREST antibody, RCOR antibody, Rcor1 antibody, RCOR1_HUMAN antibody, REST corepressor 1 antibody, Retinoic acid receptor RXR-beta antibody, Retinoid X receptor beta antibody, Rxrb antibody

    UniProt
    Q9UKL0
    途径
    Regulation of Hormone Metabolic Process, Chromatin Binding
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