RTEL1 抗体 (AA 975-1219)
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- 抗原 See all RTEL1 抗体
- RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))
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抗原表位
- AA 975-1219
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RTEL1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Regulator of telomere elongation helicase 1 protein (975-1219AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))
- 别名
- RTEL1 (RTEL1 产品)
- 别名
- F18B13.3 antibody, F18B13_3 antibody, C20orf41 antibody, DKCB5 antibody, NHL antibody, RTEL antibody, bK3184A7.3 antibody, AI451565 antibody, AW540478 antibody, Rtel antibody, RGD1306721 antibody, zgc:113114 antibody, regulator of telomere elongation helicase 1 antibody, RAD3-like DNA-binding helicase protein antibody, RTEL1 antibody, rtel1 antibody, AT1G79950 antibody, LOC100286037 antibody, Rtel1 antibody
- 背景
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Background: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
Aliases: RTEL1 antibody, C20orf41 antibody, KIAA1088 antibody, NHLRegulator of telomere elongation helicase 1 antibody, EC 3.6.4.12 antibody, Novel helicase-like antibody
- UniProt
- Q9NZ71
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