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UPF3B 抗体 (AA 319-423)

UPF3B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167644
发货至: 中国
  • 抗原 See all UPF3B 抗体
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 319-423
    适用
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    This UPF3B antibody is un-conjugated
    应用范围
    • 10
    • 5
    • 4
    • 3
    • 2
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Regulator of nonsense transcripts 3B protein (319-423AA)
    亚型
    IgG
    Top Product
    Discover our top product UPF3B Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    UPF3B (UPF3 Regulator of Nonsense Transcripts Homolog B (UPF3B))
    别名
    UPF3B (UPF3B 产品)
    别名
    HUPF3B antibody, MRXS14 antibody, RENT3B antibody, UPF3X antibody, 5730594O13Rik antibody, AI317193 antibody, AW541158 antibody, RGD1560264 antibody, UPF3B, regulator of nonsense mediated mRNA decay antibody, UPF3 regulator of nonsense transcripts homolog B (yeast) antibody, UPF3B antibody, Upf3b antibody
    背景

    Background: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-exon junctions. In vitro, stimulates translation, the function is independent of association with UPF2 and components of the EJC core.

    Aliases: UPF3B antibody, RENT3B antibody, UPF3X antibody, Regulator of nonsense transcripts 3B antibody, Nonsense mRNA reducing factor 3B antibody, Up-frameshift suppressor 3 homolog B antibody, hUpf3B antibody, Up-frameshift suppressor 3 homolog on chromosome X antibody, hUpf3p-X antibody

    UniProt
    Q9BZI7
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