RIPK3 抗体 (AA 1-120)
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- 抗原 See all RIPK3 抗体
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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抗原表位
- AA 1-120
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIPK3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Receptor-interacting serine/threonine-protein kinase 3 protein (1-120AA)
- 亚型
- IgG
- Top Product
- Discover our top product RIPK3 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- 别名
- RIPK3 (RIPK3 产品)
- 别名
- RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
- 背景
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Background: Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Aliases: Receptor interacting protein 3 antibody, Receptor interacting serine threonine kinase 3 antibody, Receptor interacting serine/threonine protein kinase 3 antibody, Receptor-interacting protein 3 antibody, Receptor-interacting serine/threonine-protein kinase 3 antibody, RIP 3 antibody, RIP like protein kinase 3 antibody, RIP-3 antibody, RIP-like protein kinase 3 antibody, RIPK 3 antibody, RIPK3 antibody, RIPK3_HUMAN antibody
- UniProt
- Q9Y572
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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