RAB5 抗体 (AA 1-215)
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- 抗原 See all RAB5 (RAB5A) 抗体
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
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抗原表位
- AA 1-215
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAB5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ras-related protein Rab-5A protein (1-215AA)
- 亚型
- IgG
- Top Product
- Discover our top product RAB5A Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
- 别名
- RAB5A (RAB5A 产品)
- 背景
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Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
Aliases: RAB 5 antibody, RAB 5A antibody, RAB5A antibody, RAB5A member RAS oncogene family antibody, RAB5A_HUMAN antibody, RAS associated protein RAB5A antibody, Ras related protein Rab 5A antibody, Ras-related protein Rab-5A antibody
- UniProt
- P20339
- 途径
- Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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