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RAB5 抗体 (AA 1-215)

RAB5A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167354
发货至: 中国
  • 抗原 See all RAB5 (RAB5A) 抗体
    RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
    抗原表位
    • 15
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    AA 1-215
    适用
    • 90
    • 62
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    • 11
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    宿主
    • 94
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    克隆类型
    • 88
    • 19
    多克隆
    标记
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    This RAB5 antibody is un-conjugated
    应用范围
    • 77
    • 32
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    • 16
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    • 7
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ras-related protein Rab-5A protein (1-215AA)
    亚型
    IgG
    Top Product
    Discover our top product RAB5A Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))
    别名
    RAB5A (RAB5A 产品)
    背景

    Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).

    Aliases: RAB 5 antibody, RAB 5A antibody, RAB5A antibody, RAB5A member RAS oncogene family antibody, RAB5A_HUMAN antibody, RAS associated protein RAB5A antibody, Ras related protein Rab 5A antibody, Ras-related protein Rab-5A antibody

    UniProt
    P20339
    途径
    Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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