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RRAGA 抗体 (AA 1-247)

RRAGA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167205
发货至: 中国
  • 抗原 See all RRAGA 抗体
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    抗原表位
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-247
    适用
    • 28
    • 12
    • 12
    • 1
    宿主
    • 28
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 11
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RRAGA antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ras-related GTP-binding protein A protein (1-247AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RRAGA (Ras-Related GTP Binding A (RRAGA))
    别名
    RRAGA (RRAGA 产品)
    别名
    FIP-1 antibody, FIP1 antibody, RAGA antibody, 1300010C19Rik antibody, AI255374 antibody, Raga antibody, Ras related GTP binding A antibody, Ras-related GTP binding A antibody, RRAGA antibody, Rraga antibody
    背景

    Background: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.

    Aliases: Adenovirus E3 14.7 kDa-interacting protein 1 antibody, FIP-1 antibody, Rag A antibody, RagA antibody, Ras-related GTP-binding protein A antibody, RRAGA antibody, RRAGA_HUMAN antibody

    UniProt
    Q7L523
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