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RAC1 抗体 (AA 11-185) (Biotin)

适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7167197
发货至: 中国
  • 抗原 See all RAC1 抗体
    RAC1
    抗原表位
    • 18
    • 15
    • 10
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-185
    适用
    • 82
    • 52
    • 37
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 74
    • 7
    • 1
    克隆类型
    • 74
    • 8
    多克隆
    标记
    • 36
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAC1 antibody is conjugated to Biotin
    应用范围
    • 57
    • 26
    • 26
    • 21
    • 15
    • 11
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Ras-related C3 botulinum toxin substrate 1 protein (11-185AA)
    亚型
    IgG
    Top Product
    Discover our top product RAC1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RAC1
    Abstract
    RAC1 产品
    别名
    Rac-1 antibody, TC-25 antibody, p21-Rac1 antibody, AL023026 antibody, D5Ertd559e antibody, RAC2 antibody, CRAC1A antibody, rac1 antibody, wu:fd16e02 antibody, zgc:55823 antibody, zgc:55917 antibody, zgc:86934 antibody, 2248 antibody, CG2248 antibody, D-Rac antibody, D-Rac 1 antibody, D-Rac1 antibody, DRac antibody, DRac1 antibody, DRacA antibody, Dm Rac1 antibody, DmRAC antibody, DmRAC1 antibody, Dmel\CG2248 antibody, Dmrac1 antibody, Drac antibody, Drac1 antibody, Drac1a antibody, DracA antibody, GTPase Rac1 antibody, P40792 antibody, RAC1 antibody, Rac antibody, Rac GTPase antibody, Rac3 antibody, RacA antibody, dRac antibody, dRac1 antibody, drac1 antibody, rac antibody, Xrac antibody, mig5 antibody, p21-rac1 antibody, tc-25 antibody, Rac family small GTPase 1 antibody, RAS-related C3 botulinum substrate 1 antibody, ras-related C3 botulinum toxin substrate 1 antibody, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody, Rac family small GTPase 1a antibody, CG2248 gene product from transcript CG2248-RB antibody, Rac family small GTPase 1 L homeolog antibody, ras homolog family member G antibody, RAC1 antibody, Rac1 antibody, rac1a antibody, rac1.L antibody, RHOG antibody
    背景

    Background: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In glioma cells, promotes cell migration and invasion. In podocytes, promotes nuclear shuttling of NR3C2, this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3.

    Aliases: Cell migration inducing gene 5 protein antibody, Cell migration-inducing gene 5 protein antibody, MGC111543 antibody, MIG5 antibody, Migration inducing gene 5 antibody, Migration inducing protein 5 antibody, p21 Rac1 antibody, p21-Rac1 antibody, Rac 1 antibody, RAC1 antibody, RAC1_HUMAN antibody, Ras like protein TC25 antibody, Ras related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody, Ras-like protein TC25 antibody, Ras-related C3 botulinum toxin substrate 1 antibody, Rho family small GTP binding protein Rac1 antibody, TC 25 antibody, TC25 antibody

    UniProt
    P63000
    途径
    WNT signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
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