-
- 抗原 See all RASGRP1 抗体
- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
-
抗原表位
- AA 594-716
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RASGRP1 antibody is un-conjugated
-
应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human RAS guanyl-releasing protein 1 protein (594-716AA)
- 亚型
- IgG
- Top Product
- Discover our top product RASGRP1 Primary Antibody
-
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 598-797) antibody
RASGRP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 495-521) antibodyRASGRP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21940 unconjugated
anti-RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1) (AA 617-666) antibodyRASGRP1 适用: 人, 豚鼠, 小鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- RASGRP1 (RAS Guanyl Releasing Protein 1 (Calcium and DAG-Regulated) (RASGRP1))
- 别名
- RASGRP1 (RASGRP1 产品)
- 别名
- Rasgrp antibody, CALDAG-GEFI antibody, CALDAG-GEFII antibody, RASGRP antibody, V antibody, hRasGRP1 antibody, RAS guanyl releasing protein 1 antibody, Rasgrp1 antibody, RASGRP1 antibody
- 背景
-
Background: Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP (PubMed:15899849, PubMed:23908768). Activates the Erk/MAP kinase cascade (PubMed:15899849). Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras (PubMed:10807788, PubMed:12839994). Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways (PubMed:19933860). Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses (By similarity). May also function in differentiation of other cell types (PubMed:12845332).
Aliases: RASGRP1 antibody, RASGRPRAS guanyl-releasing protein 1 antibody, Calcium and DAG-regulated guanine nucleotide exchange factor II antibody, CalDAG-GEFII antibody, Ras guanyl-releasing protein antibody
- UniProt
- O95267
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
-
You are here:
