RASSF1 抗体 (AA 23-145) (FITC)
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- 抗原 See all RASSF1 抗体
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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抗原表位
- AA 23-145
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASSF1 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Ras association domain-containing protein 1 protein (23-145AA)
- 亚型
- IgG
- Top Product
- Discover our top product RASSF1 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- 别名
- RASSF1 (RASSF1 产品)
- 别名
- RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody
- 背景
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Background: Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein. Isoform C has been shown not to perform these roles, no function has been identified for this isoform. Isoform A disrupts interactions among MDM2, DAXX and USP7, thus contributing to the efficient activation of TP53 by promoting MDM2 self-ubiquitination in cell-cycle checkpoint control in response to DNA damage.
Aliases: 123F2 antibody, Cardiac specific ras association domain family 1 protein antibody, cardiac-specific ras association domain family 1 protein, 123F2 antibody, NORE2A antibody, OTTHUMP00000195503 antibody, OTTHUMP00000195504 antibody, OTTHUMP00000195505 antibody, OTTHUMP00000195507 antibody, Pancreas specific ras association domain family 1 protein antibody, Ras association (RalGDS/AF 6) domain family member 1 antibody, Ras association domain-containing protein 1 antibody, RASF1_HUMAN antibody, Rassf1 antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, Tumor suppressor protein RDA32 antibody, WUGSC:H_LUCA12.5 antibody
- UniProt
- Q9NS23
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