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- 抗原 See all RanBP3 (RANBP3) 抗体
- RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
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抗原表位
- AA 1-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RanBP3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Ran-binding protein 3 protein (1-250AA)
- 亚型
- IgG
- Top Product
- Discover our top product RANBP3 Primary Antibody
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anti-RAN Binding Protein 3 (RANBP3) (AA 298-397) antibody
RANBP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-RAN Binding Protein 3 (RANBP3) (AA 1-250) antibodyRANBP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 3 (RANBP3) antibodyRANBP3 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
- 别名
- RANBP3 (RANBP3 产品)
- 别名
- 2610024N24Rik antibody, AA408221 antibody, ranbp3 antibody, MGC79798 antibody, zgc:63485 antibody, RAN binding protein 3 antibody, RAN binding protein 3 L homeolog antibody, RAN binding protein 3a antibody, RANBP3 antibody, Ranbp3 antibody, ranbp3.L antibody, ranbp3 antibody, ranbp3a antibody
- 背景
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Background: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
Aliases: DKFZp586I1520 antibody, Ran binding protein 3 antibody, Ran-binding protein 3 antibody, RANB3_HUMAN antibody, RanBP3 antibody
- UniProt
- Q9H6Z4
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