RSAD2 抗体 (AA 42-361)
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- 抗原 See all RSAD2 抗体
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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抗原表位
- AA 42-361
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RSAD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Radical S-adenosyl methionine domain-containing protein 2 protein (42-361AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
- 别名
- RSAD2 (RSAD2 产品)
- 别名
- CIG6 antibody, RSAD2 antibody, 2510004L01Rik antibody, cig33 antibody, cig5 antibody, vig1 antibody, Vig1 antibody, Best5 antibody, si:ch211-276e8.2 antibody, zgc:112342 antibody, viperin antibody, rsad2 antibody, radical S-adenosyl methionine domain containing 2 antibody, viperin antibody, RSAD2 antibody, Rsad2 antibody, rsad2 antibody, vig1 antibody
- 背景
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Background: Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63\\\'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
Aliases: 2510004L01Rik antibody, cig 33 antibody, CIG 5 antibody, cig-33 antibody, CIG-5 antibody, CIG33 antibody, CIG5 antibody, Cytomegalovirus induced gene 5 protein antibody, Cytomegalovirus-induced gene 5 protein antibody, endoplasmic reticulum-associated antibody, interferon-inducible antibody, Radical S adenosyl methionine domain containing 2 antibody, Radical S-adenosyl methionine domain-containing protein 2 antibody, RSAD 2 antibody, Rsad2 antibody, RSAD2_HUMAN antibody, RSDA-2 antibody, VIG 1 antibody, vig1 antibody, Viperin antibody, Virus inhibitory protein antibody, virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody
- UniProt
- Q8WXG1
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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