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TIMELESS 抗体 (AA 1004-1131)

TIMELESS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7166187
发货至: 中国
  • 抗原 See all TIMELESS 抗体
    TIMELESS (Timeless Homolog (TIMELESS))
    抗原表位
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1004-1131
    适用
    • 38
    • 22
    • 18
    • 9
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 38
    • 3
    • 1
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 29
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIMELESS antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Protein timeless homolog protein (1004-1131AA)
    亚型
    IgG
    Top Product
    Discover our top product TIMELESS Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TIMELESS (Timeless Homolog (TIMELESS))
    别名
    TIMELESS (TIMELESS 产品)
    别名
    TIM antibody, TIM1 antibody, hTIM antibody, C77407 antibody, Debt69 antibody, tim antibody, CG3234 antibody, Dmel\\CG3234 antibody, Ritsu antibody, Tim antibody, dTIM antibody, dTim antibody, dtim antibody, mel_tim antibody, rit antibody, tim1 antibody, XTimeless1 antibody, timeless antibody, timelessb antibody, TIMELESS antibody, MXC20.14 antibody, MXC20_14 antibody, htim antibody, im:6903167 antibody, wu:fa95g04 antibody, wu:fd23d07 antibody, timeless circadian regulator antibody, timeless circadian clock 1 antibody, timeless antibody, timeless circadian clock antibody, timeless circadian clock S homeolog antibody, timeless family protein antibody, TIMELESS antibody, Timeless antibody, tim antibody, timeless.S antibody, Tim antibody, ATIM antibody, timeless antibody, LOC100328917 antibody
    背景

    Background: Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication and in the regulation of the circadian clock. Involved in the determination of period length and in the DNA damage-dependent phase advancing of the circadian clock. Negatively regulates CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Forms a complex with TIPIN and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. Timeless promotes TIPIN nuclear localization. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

    Aliases: FLJ12640 antibody, FLJ20714 antibody, hTIM antibody, Protein timeless homolog antibody, TIM antibody, TIM_HUMAN antibody, TIM1 antibody, Timeless antibody, timeless circadian clock 1 antibody, timeless circadian clock antibody, timeless homolog antibody, TIMELESS1 antibody, Tof1 homolog antibody

    UniProt
    Q9UNS1
    途径
    Protein targeting to Nucleus, Photoperiodism
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