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POGLUT1 抗体 (AA 132-392)

POGLUT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7165879
发货至: 中国
  • 抗原 See all POGLUT1 抗体
    POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    AA 132-392
    适用
    • 22
    • 16
    • 2
    • 1
    • 1
    宿主
    • 36
    • 1
    克隆类型
    • 36
    • 1
    多克隆
    标记
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POGLUT1 antibody is un-conjugated
    应用范围
    • 33
    • 18
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Protein O-glucosyltransferase 1 protein (132-392AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))
    别名
    POGLUT1 (POGLUT1 产品)
    别名
    C3orf9 antibody, CLP46 antibody, KDELCL1 antibody, KTELC1 antibody, MDSRP antibody, Rumi antibody, hCLP46 antibody, MDS010 antibody, 9630046K23Rik antibody, Ktelc1 antibody, protein O-glucosyltransferase 1 antibody, POGLUT1 antibody, Poglut1 antibody
    背景

    Background: Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (PubMed:27807076). Notch glucosylation does not affect Notch ligand binding (PubMed:21490058). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity).

    Aliases: C3orf9 antibody, CAP10 like 46 kDa protein antibody, CAP10 like protein, 46 kDa antibody, CAP10-like 46 kDa protein antibody, CLP46 antibody, hCLP46 antibody, hRumi antibody, KDELC family like 1 antibody, KDELCL1 antibody, KTEL (Lys Tyr Glu Leu) containing 1 antibody, KTEL motif containing protein 1 antibody, KTEL motif-containing protein 1 antibody, KTEL1 antibody, KTELC1 antibody, MDS010 antibody, MDSRP antibody, Myelodysplastic syndromes relative protein antibody, O-glucosyltransferase rumi homolog antibody, PGLT1_HUMAN antibody, Poglut1 antibody, protein O glucosyltransferase 1 antibody, Protein O-glucosyltransferase 1 antibody, Protein O-xylosyltransferase antibody, Rumi antibody, x 010 protein antibody

    UniProt
    Q8NBL1
    途径
    Notch Signaling
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