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IWS1 抗体 (AA 570-819)

IWS1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7363315
发货至: 中国
  • 抗原 See all IWS1 products
    IWS1 (IWS1 Homolog (IWS1))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 570-819
    适用
    • 18
    • 13
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 18
    克隆类型
    • 17
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IWS1 antibody is un-conjugated
    应用范围
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Protein IWS1 homolog protein (570-819AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    IWS1 (IWS1 Homolog (IWS1))
    别名
    IWS1 (IWS1 产品)
    别名
    1700069O15Rik antibody, 3000008H23 antibody, AL117927 antibody, AW214353 antibody, RGD1304762 antibody, IWS1, SUPT6H interacting protein antibody, IWS1, SUPT6 interacting protein antibody, IWS1 antibody, Iws1 antibody
    背景

    Background: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

    Aliases: DKFZp761G0123 antibody, FLJ10006 antibody, FLJ14655 antibody, FLJ32319 antibody, Interacts with Spt6 antibody, iws1 antibody, IWS1 homolog antibody, IWS1-like protein antibody, IWS1_HUMAN antibody, IWS1L antibody, MGC126375 antibody, MGC126376 antibody, OTTHUMP00000162262 antibody, Protein IWS1 homolog antibody

    UniProt
    Q96ST2
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