INTU 抗体 (AA 6-139)
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- 抗原 See all INTU 抗体
- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
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抗原表位
- AA 6-139
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INTU antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Protein inturned protein (6-139AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
- 别名
- INTU (INTU 产品)
- 别名
- 9230116I04Rik antibody, 9430087H23Rik antibody, Pdzd6 antibody, Pdzk6 antibody, mKIAA1284 antibody, INT antibody, PDZD6 antibody, PDZK6 antibody, Xint antibody, in antibody, int antibody, pdzd6 antibody, inturned planar cell polarity protein antibody, inturned planar cell polarity protein S homeolog antibody, Intu antibody, INTU antibody, intu antibody, intu.S antibody
- 背景
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Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).
Aliases: Homolog of inturned (X. tropicalis) antibody, INT antibody, intu antibody, Inturned planar cell polarity effector homolog antibody, KIAA1284 antibody, PDZ domain containing 6 antibody, PDZ domain-containing protein 6 antibody, PDZD 6 antibody, PDZD6_HUMAN antibody, PDZK6 antibody
- UniProt
- Q9ULD6
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