HOOK3 抗体 (AA 357-455) (Biotin)
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- 抗原 See all HOOK3 抗体
- HOOK3 (Hook Homolog 3 (HOOK3))
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抗原表位
- AA 357-455
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HOOK3 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Protein Hook homolog 3 protein (357-455AA)
- 亚型
- IgG
- Top Product
- Discover our top product HOOK3 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- HOOK3 (Hook Homolog 3 (HOOK3))
- 别名
- HOOK3 (HOOK3 产品)
- 别名
- 5830454D03Rik antibody, AI317159 antibody, E330005F07Rik antibody, HK3 antibody, hook3 antibody, hook microtubule-tethering protein 3 antibody, hook microtubule tethering protein 3 antibody, hook microtubule-tethering protein 3 L homeolog antibody, Hook3 antibody, HOOK3 antibody, hook3.L antibody
- 背景
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Background: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking (By similarity). Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Aliases: FLJ31058 antibody, h-hook3 antibody, hHK3 antibody, HK3 antibody, hook3 antibody, HOOK3_HUMAN antibody, OTTHUMP00000229200 antibody, Protein Hook homolog 3 antibody
- UniProt
- Q86VS8
- 途径
- Stem Cell Maintenance, Maintenance of Protein Location
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