PSMA7 抗体 (AA 5-232) (HRP)
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- 抗原 See all PSMA7 抗体
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
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抗原表位
- AA 5-232
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMA7 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Proteasome subunit alpha type-7 protein (5-232AA)
- 亚型
- IgG
- Top Product
- Discover our top product PSMA7 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
- 别名
- PSMA7 (PSMA7 产品)
- 别名
- C6 antibody, HSPC antibody, RC6-1 antibody, XAPC7 antibody, C6-I antibody, DDBDRAFT_0185059 antibody, DDBDRAFT_0217080 antibody, DDB_0185059 antibody, DDB_0217080 antibody, hspc antibody, rc6-1 antibody, xapc7 antibody, psma7 antibody, psma4-B antibody, proteasome subunit alpha 7 antibody, proteasome (prosome, macropain) subunit, alpha type 7 antibody, 20S proteasome subunit alpha-7 antibody, proteasome subunit alpha 7 S homeolog antibody, proteasome subunit alpha 7 L homeolog antibody, PSMA7 antibody, Psma7 antibody, psmA7 antibody, psma7 antibody, psma7.S antibody, psma7.L antibody
- 背景
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Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response
Aliases: C6 antibody, HSPC antibody, MGC3755 antibody, OTTHUMP00000031449 antibody, OTTHUMP00000031450 antibody, OTTHUMP00000031453 antibody, Proteasome (prosome macropain) subunit alpha type 7 antibody, Proteasome alpha 7 subunit antibody, Proteasome subunit alpha 4 antibody, Proteasome subunit alpha type 7 antibody, Proteasome subunit alpha type-7 antibody, Proteasome subunit RC6 1 antibody, Proteasome subunit RC6-1 antibody, Proteasome subunit XAPC7 antibody, PSA7_HUMAN antibody, PSMA 7 antibody, PSMA7 antibody, RC6 1 antibody, XAPC7 antibody
- UniProt
- O14818
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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