DDX5 抗体 (AA 1-290)
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- 抗原 See all DDX5 抗体
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
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抗原表位
- AA 1-290
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDX5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Probable ATP-dependent RNA helicase DDX5 protein (1-290AA)
- 亚型
- IgG
- Top Product
- Discover our top product DDX5 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DDX5 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 5 (DDX5))
- 别名
- DDX5 (DDX5 产品)
- 别名
- G17P1 antibody, HLR1 antibody, HUMP68 antibody, p68 antibody, 2600009A06Rik antibody, Hlr1 antibody, wu:fa56a07 antibody, wu:fb11e01 antibody, wu:fb16c10 antibody, wu:fb53b05 antibody, ddx5 antibody, DEAD-box helicase 5 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 antibody, DEAD (Asp-Glu-Ala-Asp) box helicase 5 antibody, DEAD-box helicase 5 L homeolog antibody, DDX5 antibody, Ddx5 antibody, ddx5 antibody, ddx5.L antibody
- 背景
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Background: Involved in the alternative regulation of pre-mRNA splicing, its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation, the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specicic manner, the function probbaly involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3\\\' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
Aliases: ATP dependent RNA helicase DDX5 antibody, DDX 5 antibody, Ddx5 antibody, DDX5_HUMAN antibody, DEAD (Asp Glu Ala Asp) box helicase 5 antibody, DEAD (Asp Glu Ala Asp) box polypeptide 5 antibody, DEAD box 5 antibody, DEAD box protein 5 antibody, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase, 68kD) antibody, G17P1 antibody, HELR antibody, HLR1 antibody, HUMP68 antibody, P68 antibody, p68 RNA helicase antibody, Probable ATP dependent RNA helicase DDX5 antibody, Probable ATP-dependent RNA helicase DDX5 antibody, RNA helicase p68 antibody
- UniProt
- P17844
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Response to DNA Damage Stimulus
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