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- 抗原 See all Presenilin 1 (PSEN1) 抗体
- Presenilin 1 (PSEN1)
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抗原表位
- AA 1-160
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Presenilin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Presenilin-1 protein (1-160AA)
- 亚型
- IgG
- Top Product
- Discover our top product PSEN1 Primary Antibody
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anti-Presenilin 1 (PSEN1) (AA 1-160) antibody
PSEN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 330-359), (C-Term) antibodyPSEN1 适用: 人, 小鼠 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB2257 unconjugated
anti-Presenilin 1 (PSEN1) (AA 4-218) antibodyPSEN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (Middle Region) antibodyPSEN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Presenilin 1 (PSEN1) (AA 1-100) antibody (FITC)PSEN1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal FITC
anti-Presenilin 1 (PSEN1) (AA 1-100) antibody (Alkaline Phosphatase (AP))PSEN1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Presenilin 1 (PSEN1) (AA 100-200) antibody (Biotin)PSEN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-Presenilin 1 (PSEN1) (AA 100-200) antibody (PE)PSEN1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal PE
anti-Presenilin 1 (PSEN1) (AA 1-100) antibody (APC)PSEN1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal APC
anti-Presenilin 1 (PSEN1) (AA 300-349) antibodyPSEN1 适用: 人, 小鼠, 猴, Cow, Pig, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Presenilin 1 (PSEN1)
- 别名
- PSEN1 (PSEN1 产品)
- 别名
- pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
- 背景
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Background: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis.
Aliases: AD3 antibody, Ad3h antibody, FAD antibody, Homo Sapiens Clone CC44 Senilin 1 antibody, Presenilin-1 CTF12 antibody, Protein S182 antibody, PS 1 antibody, PS-1 antibody, PS1-CTF12 antibody, PSEN1 antibody, PSN1_HUMAN antibody, PSNL1 antibody, S182 antibody
- UniProt
- P49768
- 途径
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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