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Lamin A/C 抗体 (AA 385-572)

LMNA 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7164247
发货至: 中国
  • 抗原 See all Lamin A/C (LMNA) 抗体
    Lamin A/C (LMNA)
    抗原表位
    • 10
    • 8
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    AA 385-572
    适用
    • 131
    • 73
    • 71
    • 27
    • 15
    • 13
    • 8
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    • 6
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    宿主
    • 96
    • 45
    • 2
    • 1
    克隆类型
    • 95
    • 49
    多克隆
    标记
    • 113
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    This Lamin A/C antibody is un-conjugated
    应用范围
    • 119
    • 54
    • 53
    • 47
    • 32
    • 31
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    • 20
    • 15
    • 7
    • 3
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Prelamin-A/C protein (385-572AA)
    亚型
    IgG
    Top Product
    Discover our top product LMNA Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Lamin A/C (LMNA)
    别名
    LMNA (LMNA 产品)
    背景

    Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.

    Aliases: 70 kDa lamin antibody, Cardiomyopathy dilated 1A (autosomal dominant) antibody, CDCD1 antibody, CDDC antibody, CMD1A antibody, CMT2B1 antibody, EMD2 antibody, FPL antibody, FPLD antibody, FPLD2 antibody, HGPS antibody, IDC antibody, Lamin A antibody, Lamin A/C antibody, Lamin A/C like 1 antibody, Lamin antibody, Lamin C antibody, lamin-a antibody, Lamin-A/C antibody, LDP1 antibody, LFP antibody, LGMD1B antibody, Limb girdle muscular dystrophy 1B (autosomal dominant) antibody, LMN 1 antibody, LMN A antibody, LMN C antibody, LMN1 antibody, LMNA antibody, LMNA_HUMAN antibody, LMNC antibody, LMNL1 antibody, Prelamin A/C antibody, PRO1 antibody, Renal carcinoma antigen NY REN 32 antibody, Renal carcinoma antigen NY-REN-32 antibody, Renal carcinoma antigen NYREN32 antibody

    UniProt
    P02545
    途径
    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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