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PBX1 抗体 (AA 315-430)

PBX1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7164137
发货至: 中国
  • 抗原 See all PBX1 抗体
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    抗原表位
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-430
    适用
    • 24
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    宿主
    • 15
    • 8
    • 1
    克隆类型
    • 17
    • 7
    多克隆
    标记
    • 20
    • 2
    • 1
    • 1
    This PBX1 antibody is un-conjugated
    应用范围
    • 18
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    人, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA)
    亚型
    IgG
    Top Product
    Discover our top product PBX1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:100-1:300, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
    别名
    PBX1 (PBX1 产品)
    别名
    fi29e01 antibody, pbx1b antibody, wu:fi29e01 antibody, zgc:55265 antibody, 2310056B04Rik antibody, AI848790 antibody, AU015730 antibody, D230003C07Rik antibody, Pbx-1 antibody, Pbx1a antibody, Pbx1b antibody, PBX1A antibody, Xpbx1 antibody, Xpbx1b antibody, PBX homeobox 1 antibody, pre-B-cell leukemia homeobox 1a antibody, pre B cell leukemia homeobox 1 antibody, pre-B-cell leukemia homeobox 1 S homeolog antibody, PBX1 antibody, pbx1a antibody, Pbx1 antibody, pbx1.S antibody
    背景

    Background: Binds the sequence 5\\\'-ATCAATCAA-3\\\'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1,19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).

    Aliases: DKFZp686B09108 antibody, Homeo box protein PBX1 antibody, Homeo box protein PRL antibody, Homeobox protein PBX 1 antibody, Homeobox protein PBX1 antibody, Homeobox protein PRL antibody, MGC126627 antibody, PBX 1 antibody, Pbx1 antibody, PBX1_HUMAN antibody, Pre B cell leukemia homeobox 1 antibody, Pre B cell leukemia transcription factor 1 antibody, Pre-B-cell leukemia transcription factor 1 antibody, PRL antibody

    UniProt
    P40424
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