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PCGF1 抗体 (AA 113-187) (HRP)

PCGF1 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7163797
发货至: 中国
  • 抗原 See all PCGF1 抗体
    PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))
    抗原表位
    • 15
    • 15
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 113-187
    适用
    • 29
    • 19
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 43
    • 1
    克隆类型
    • 44
    多克隆
    标记
    • 12
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PCGF1 antibody is conjugated to HRP
    应用范围
    • 40
    • 26
    • 26
    • 11
    • 6
    • 6
    • 2
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Polycomb group RING finger protein 1 protein (113-187AA)
    亚型
    IgG
    Top Product
    Discover our top product PCGF1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PCGF1 (Polycomb Group Ring Finger 1 (PCGF1))
    别名
    PCGF1 (PCGF1 产品)
    别名
    PCGF1 antibody, 2010002K04Rik antibody, NSPC1 antibody, RNF3A-2 antibody, RNF68 antibody, AU024121 antibody, Nspc1 antibody, nspc1 antibody, si:zc207o21.2 antibody, polycomb group ring finger 1 antibody, polycomb group ring finger 1 L homeolog antibody, PCGF1 antibody, pcgf1 antibody, Pcgf1 antibody, pcgf1.L antibody
    背景

    Background: Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6, this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \'Lys-119\', rendering chromatin heritably changed in its expressibility. Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells (PubMed:26687479).

    Aliases: PCGF1 antibody, NSPC1 antibody, RNF68 antibody, Polycomb group RING finger protein 1 antibody, Nervous system Polycomb-1 antibody, NSPc1 antibody, RING finger protein 68 antibody

    UniProt
    Q9BSM1
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