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- 抗原 See all PARG 抗体
- PARG
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抗原表位
- AA 1-348
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARG antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Poly(ADP-ribose) glycohydrolase protein (1-348AA)
- 亚型
- IgG
- Top Product
- Discover our top product PARG Primary Antibody
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anti-PARG (PARG) (AA 1-976) antibody
PARG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PARG (PARG) antibodyPARG 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-PARG (PARG) (AA 770-819) antibodyPARG 适用: 人, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-PARG (PARG) (AA 777-976) antibodyPARG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PARG (PARG) (AA 390-421), (C-Term) antibodyPARG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14201-RB14549 unconjugated
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PARG
- 别名
- PARG (PARG 产品)
- 别名
- PARG99 antibody, AI413217 antibody, poly(ADP-ribose) glycohydrolase antibody, poly (ADP-ribose) glycohydrolase antibody, PARG antibody, Parg antibody
- 背景
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Background: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP-ribose monomers (PubMed:23102699). Required for retinoid acid-dependent gene transactivation, probably by dePARsylating histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters (PubMed:23102699). Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257).
Aliases: ADP riboseglycohydrolase antibody, Mitochondrial poly(ADP ribose) glycohydrolase antibody, Parg antibody, PARG_HUMAN antibody, PARG99 antibody, Poly antibody, poly (ADP ribose) glycohydrolase antibody, poly(ADP-ribose) glycohydrolase 60 kDa isoform antibody, Poly(ADP-ribose) glycohydrolase antibody
- UniProt
- Q86W56
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