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- 抗原 See all PARN 抗体
- PARN (Poly A Specific Ribonuclease (PARN))
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抗原表位
- AA 1-639
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Poly(A)-specific ribonuclease PARN protein (1-639AA)
- 亚型
- IgG
- Top Product
- Discover our top product PARN Primary Antibody
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anti-Poly A Specific Ribonuclease (PARN) (AA 1-639) antibody
PARN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-301) antibodyPARN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 501-599) antibodyPARN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (AA 1-280) antibodyPARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) antibodyPARN 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poly A Specific Ribonuclease (PARN) (C-Term) antibodyPARN 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PARN (Poly A Specific Ribonuclease (PARN))
- 别名
- PARN (PARN 产品)
- 别名
- parn-A antibody, xparn antibody, DAN antibody, RGD1565449 antibody, zgc:56067 antibody, 1200003I18Rik antibody, poly(A)-specific ribonuclease L homeolog antibody, poly(A)-specific ribonuclease antibody, poly(A)-specific ribonuclease (deadenylation nuclease) antibody, parn.L antibody, PARN antibody, Parn antibody, parn antibody
- 背景
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Background: 3\\\'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. Interacts with both the 3\\\'-end poly(A) tail and the 5\\\'-end cap structure during degradation, the interaction with the cap structure being required for an efficient degradation of poly(A) tails. Involved in nonsense-mediated mRNA decay, a critical process of selective degradation of mRNAs that contain premature stop codons. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3\\\'-UTR, possibly via its interaction with KHSRP. Probably mediates the removal of poly(A) tails of AREs mRNAs, which constitutes the first step of destabilization.
Aliases: DAN antibody, Deadenylating nuclease antibody, Deadenylation nuclease antibody, PARN antibody, PARN_HUMAN antibody, Poly A specific ribonuclease antibody, Poly(A) specific ribonuclease antibody, Poly(A)-specific ribonuclease PARN antibody, Polyadenylate specific ribonuclease antibody, Polyadenylate-specific ribonuclease antibody
- UniProt
- O95453
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