PLEKHO1 抗体 (AA 143-404)
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- 抗原 See all PLEKHO1 抗体
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
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抗原表位
- AA 143-404
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLEKHO1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Pleckstrin homology domain-containing family O member 1 protein (143-404AA)
- 亚型
- IgG
- Top Product
- Discover our top product PLEKHO1 Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
- 别名
- PLEKHO1 (PLEKHO1 产品)
- 别名
- CKIP-1 antibody, OC120 antibody, 2810052M02Rik antibody, Ckip1 antibody, JZA-20 antibody, Jza2 antibody, RGD1311487 antibody, ckip-1 antibody, plekho1 antibody, si:dkey-200h23.2 antibody, pleckstrin homology domain containing O1 antibody, pleckstrin homology domain containing, family O member 1 antibody, pleckstrin homology domain containing, family O member 1a antibody, PLEKHO1 antibody, Plekho1 antibody, plekho1a antibody
- 背景
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Background: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
Aliases: C-Jun-binding protein antibody, Casein kinase 2-interacting protein 1 antibody, CK2 interacting protein 1 antibody, CK2 interacting protein 1 HQ0024c protein antibody, CK2-interacting protein 1 antibody, CKIP 1 antibody, CKIP-1 antibody, CKIP1 antibody, JBP antibody, OC120 antibody, Osteoclast maturation associated gene 120 protein antibody, Osteoclast maturation-associated gene 120 protein antibody, PH domain-containing family O member 1 antibody, PKHO1_HUMAN antibody, Pleckstrin homology domain containing family O member 1 antibody, Pleckstrin homology domain-containing family O member 1 antibody, PLEKHO1 antibody
- UniProt
- Q53GL0
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