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PIWIL4 抗体 (AA 12-235) (Biotin)

PIWIL4 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7163479
发货至: 中国
  • 抗原 See all PIWIL4 抗体
    PIWIL4 (Piwi-Like 4 (PIWIL4))
    抗原表位
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-235
    适用
    • 29
    • 12
    • 12
    • 1
    宿主
    • 27
    • 2
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This PIWIL4 antibody is conjugated to Biotin
    应用范围
    • 13
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Piwi-like protein 4 protein (12-235AA)
    亚型
    IgG
    Top Product
    Discover our top product PIWIL4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PIWIL4 (Piwi-Like 4 (PIWIL4))
    别名
    PIWIL4 (PIWIL4 产品)
    别名
    HIWI2 antibody, MIWI2 antibody, 9230101H05Rik antibody, Miwi2 antibody, piwi like RNA-mediated gene silencing 4 antibody, piwi-like RNA-mediated gene silencing 4 antibody, PIWIL4 antibody, Piwil4 antibody
    背景

    Background: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association. The piRNA process acts upstream of known mediators of DNA methylation. Participates in a piRNA amplification loop. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity). May be involved in the chromatin-modifying pathway by inducing \'Lys-9\' methylation of histone H3 at some loci (PubMed:12906857).

    Aliases: DKFZp686P01248 antibody, FLJ36156 antibody, HILI 2 antibody, HILI2 antibody, HIWI 2 antibody, HIWI2 antibody, Miwi 2 protein antibody, Miwi2 antibody, PIWI antibody, Piwi like 2 antibody, Piwi like 4 (Drosophila) antibody, Piwi like 4 antibody, Piwi like protein 4 antibody, PIWI like protein antibody, Piwi like RNA mediated gene silencing 4 antibody, Piwi-like protein 4 antibody, PIWIL 4 antibody, Piwil4 antibody, PIWL4_HUMAN antibody

    UniProt
    Q7Z3Z4
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