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NOXA 抗体 (AA 1-136)

PMAIP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7163088
发货至: 中国
  • 抗原 See all NOXA (PMAIP1) 抗体
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    抗原表位
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1-136
    适用
    • 30
    • 4
    • 2
    宿主
    • 23
    • 6
    • 1
    • 1
    克隆类型
    • 18
    • 13
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NOXA antibody is un-conjugated
    应用范围
    • 12
    • 9
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA)
    亚型
    IgG
    Top Product
    Discover our top product PMAIP1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    别名
    PMAIP1 (PMAIP1 产品)
    别名
    TN3 antibody, PMAIP1 antibody, zgc:162379 antibody, APR antibody, NOXA antibody, Noxa antibody, phorbol-12-myristate-13-acetate-induced protein 1 antibody, PMAIP1 antibody, pmaip1 antibody, Pmaip1 antibody
    背景

    Background: Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

    Aliases: Adult T cell leukemia derived PMA responsive antibody, APR antibody, APR_HUMAN antibody, ATL-derived antibody, Immediate early response protein APR antibody, Immediate-early-response protein APR antibody, NOXA antibody, Phorbol 12 myristate 13 acetate induced protein 1 antibody, Phorbol-12-myristate-13-acetate-induced protein 1 antibody, PMA induced protein 1 antibody, PMA-induced protein 1 antibody, PMA-responsive gene antibody, Pmaip1 antibody, Protein Noxa antibody

    UniProt
    Q13794
    途径
    p53 Pathway, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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