PHF1 抗体 (AA 151-360)
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- 抗原 See all PHF1 抗体
- PHF1 (PHD Finger Protein 1 (PHF1))
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抗原表位
- AA 151-360
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human PHD finger protein 10 protein (151-360AA)
- 亚型
- IgG
- Top Product
- Discover our top product PHF1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PHF1 (PHD Finger Protein 1 (PHF1))
- 别名
- PHF1 (PHF1 产品)
- 别名
- pcl1 antibody, xpcl1 antibody, MTF2L2 antibody, PCL1 antibody, PHF2 antibody, TDRD19C antibody, hPHF1 antibody, AW557215 antibody, D17Ertd455e antibody, Tctex-3 antibody, Tctex3 antibody, mPcl1 antibody, PHD finger protein 1 L homeolog antibody, PHD finger protein 1 antibody, phf1.L antibody, PHF1 antibody, Phf1 antibody
- 背景
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Background: Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Aliases: BAF45a antibody, BRG1-associated factor 45a antibody, FLJ10975 antibody, MGC111009 antibody, PHD finger protein 10 antibody, PHD finger protein 10, isoform a antibody, PHD zinc finger protein XAP135 antibody, Phf10 antibody, PHF10_HUMAN antibody, XAP135 antibody
- UniProt
- Q8WUB8
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