PCID2 抗体 (AA 2-250)
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- 抗原 See all PCID2 抗体
- PCID2 (PCI Domain Containing 2 (PCID2))
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抗原表位
- AA 2-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PCID2 antibody is un-conjugated
- 应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human PCI domain-containing protein 2 protein (2-250AA)
- 亚型
- IgG
- Top Product
- Discover our top product PCID2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PCID2 (PCI Domain Containing 2 (PCID2))
- 别名
- PCID2 (PCID2 产品)
- 别名
- F10 antibody, RGD1307041 antibody, A730042J05Rik antibody, ik:tdsubc_1e10 antibody, im:6909928 antibody, wu:fa11f03 antibody, xx:tdsubc_1e10 antibody, zgc:101845 antibody, PCI domain containing 2 antibody, PCI domain containing 2 S homeolog antibody, PCID2 antibody, Pcid2 antibody, pcid2.S antibody, pcid2 antibody
- 背景
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Background: Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells.
Aliases: CSN12 like protein antibody, CSN12-like protein antibody, DKFZp686C20226 antibody, F10 antibody, FLJ11305 antibody, FLJ99362 antibody, HT004 antibody, MGC16774 antibody, PCI domain containing 2 antibody, PCI domain containing protein 2 antibody, PCI domain-containing protein 2 antibody, PCID2 antibody, PCID2_HUMAN antibody, RP11 - 98F14.6 antibody
- UniProt
- Q5JVF3
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