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OLR1 抗体 (AA 58-273)

OLR1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7162378
发货至: 中国
  • 抗原 See all OLR1 抗体
    OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
    抗原表位
    • 16
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 58-273
    适用
    • 57
    • 24
    • 21
    • 18
    • 2
    宿主
    • 43
    • 18
    • 2
    • 1
    • 1
    • 1
    克隆类型
    • 47
    • 19
    多克隆
    标记
    • 32
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This OLR1 antibody is un-conjugated
    应用范围
    • 43
    • 23
    • 19
    • 13
    • 13
    • 10
    • 10
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Oxidized low-density lipoprotein receptor 1 protein (58-273AA)
    亚型
    IgG
    Top Product
    Discover our top product OLR1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
    别名
    OLR1 (OLR1 产品)
    别名
    OLR1 antibody, LOX1 antibody, Olr1 antibody, CLEC8A antibody, LOXIN antibody, SCARE1 antibody, SLOX1 antibody, LOX-1 antibody, SR-EI antibody, Scare1 antibody, Oldlr1 antibody, Oldr1 antibody, PLOX-1 antibody, oxidized low density lipoprotein receptor 1 antibody, oxidized low density lipoprotein (lectin-like) receptor 1 antibody, OLR1 antibody, Olr1 antibody
    背景

    Background: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

    Aliases: C-type lectin domain family 8 member A antibody, CLEC8A antibody, hLOX 1 antibody, hLOX-1 antibody, Lectin like oxidized LDL receptor 1 antibody, Lectin like oxLDL receptor 1 antibody, Lectin type oxidized LDL receptor 1 antibody, Lectin-like oxidized LDL receptor 1 antibody, Lectin-like oxLDL receptor 1 antibody, Lectin-type oxidized LDL receptor 1 antibody, low density lipoprotein oxidized, receptor 1 antibody, LOX-1 antibody, LOXIN antibody, Olr1 antibody, OLR1_HUMAN antibody, Ox LDL receptor 1 antibody, Ox-LDL receptor 1 antibody, Oxidised low density lipoprotein (lectin like) receptor 1 antibody, Oxidized low density lipoprotein receptor 1 antibody, Oxidized low density lipoprotein receptor 1 soluble form antibody, Oxidized low-density lipoprotein receptor 1 antibody, OxLDL receptor 1 antibody, SCARE1 antibody, Scavenger receptor class E, member 1 antibody, SLOX1 antibody, soluble form antibody, SR-EI antibody

    UniProt
    P78380
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