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- 抗原 See all NOD2 抗体
- NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
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抗原表位
- AA 460-733
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOD2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Nucleotide-binding oligomerization domain-containing protein 2 protein (460-733AA)
- 亚型
- IgG
- Top Product
- Discover our top product NOD2 Primary Antibody
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anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 611-910) antibody
NOD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (N-Term) antibodyNOD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 251-350) antibodyNOD2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibodyNOD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 1-1040) antibodyNOD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (C-Term) antibodyNOD2 适用: 人 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 251-350) antibody (AbBy Fluor® 488)NOD2 适用: 人 WB, FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (AA 1-1040) antibodyNOD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) (Internal Region) antibodyVerified NOD2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) antibodyNOD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NOD2 (Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2))
- 别名
- NOD2 (NOD2 产品)
- 别名
- ACUG antibody, BLAU antibody, CARD15 antibody, CD antibody, CLR16.3 antibody, IBD1 antibody, NLRC2 antibody, NOD2B antibody, PSORAS1 antibody, Card15 antibody, F830032C23Rik antibody, Nlrc2 antibody, caspase recruitment domain 15 protein antibody, nucleotide binding oligomerization domain containing 2 antibody, nucleotide-binding oligomerization domain containing 2 antibody, TTHERM_01951320 antibody, NOD2 antibody, Nod2 antibody
- 背景
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Background: Involved in gastrointestinal immunity. Upon stimulation by muramyl dipeptide (MDP), a fragment of bacterial peptidoglycan, binds the proximal adapter receptor-interacting RIPK2, which recruits ubiquitin ligases as XIAP, BIRC2, BIRC3 and the LUBAC complex, triggering activation of MAP kinases and activation of NF-kappa-B signaling. This in turn leads to the transcriptional activation of hundreds of genes involved in immune response. Required for MDP-induced NLRP1-dependent CASP1 activation and IL1B release in macrophages (PubMed:18511561).
Aliases: ACUG antibody, Arthrocutaneouveal granulomatosis antibody, BLAU antibody, CARD15 antibody, Caspase recruitment domain family, member 15 antibody, Caspase recruitment domain protein 15 antibody, Caspase recruitment domain-containing protein 15 antibody, CD antibody, CLR16.3 antibody, IBD1 antibody, Inflammatory bowel disease protein 1 antibody, LRR containing protein antibody, NLR family, CARD domain containing 2 antibody, NLRC2 antibody, NOD like receptor C2 antibody, NOD2 antibody, NOD2 protein antibody, NOD2_HUMAN antibody, NOD2B antibody, nucleotide binding oligomerization domain 2 antibody, Nucleotide binding oligomerization domain containing 2 antibody, Nucleotide binding oligomerization domain, leucine rich repeat and CARD domain containing 2 antibody, Nucleotide-binding oligomerization domain-containing protein 2 antibody, PSORAS1 antibody
- UniProt
- Q9HC29
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome
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