TR4 抗体 (AA 240-380)
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- 抗原 See all TR4 (NR2C2) 抗体
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
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抗原表位
- AA 240-380
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TR4 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Nuclear receptor subfamily 2 group C member 2 protein (240-380AA)
- 亚型
- IgG
- Top Product
- Discover our top product NR2C2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 别名
- NR2C2 (NR2C2 产品)
- 别名
- TAK1 antibody, TR2R1 antibody, TR4 antibody, hTAK1 antibody, Tr4 antibody, gb:dq017625 antibody, im:6911408 antibody, mKIAA4145 antibody, nuclear receptor subfamily 2 group C member 2 antibody, nuclear receptor subfamily 2, group C, member 2 antibody, NR2C2 antibody, Nr2c2 antibody, nr2c2 antibody
- 背景
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Background: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5\\\'-AGGTCA-3\\\' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
Aliases: hTAK1 antibody, Nr2c2 antibody, NR2C2_HUMAN antibody, Nuclear hormone receptor TR4 antibody, Nuclear receptor subfamily 2 group C member 2 antibody, Orphan nuclear receptor TAK1 antibody, Orphan nuclear receptor TR4 antibody, TAK1 antibody, Testicular nuclear receptor 4 antibody, Testicular receptor 4 antibody, TR2R1 antibody, TR4 antibody, TR4 nuclear hormone receptor antibody
- UniProt
- P49116
- 途径
- TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
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