RORB 抗体 (AA 1-269)
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- 抗原 See all RORB 抗体
- RORB (RAR-Related Orphan Receptor B (RORB))
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抗原表位
- AA 1-269
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RORB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Nuclear receptor ROR-beta protein (1-269AA)
- 亚型
- IgG
- Top Product
- Discover our top product RORB Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RORB (RAR-Related Orphan Receptor B (RORB))
- 别名
- RORB (RORB 产品)
- 别名
- RORB antibody, Nr1f2 antibody, LOC100226267 antibody, NR1F2 antibody, ROR-BETA antibody, RZR-BETA antibody, RZRB antibody, bA133M9.1 antibody, nr1f2 antibody, rzrb antibody, sb:eu943 antibody, RZR-beta antibody, Rorbeta antibody, RAR related orphan receptor B antibody, RAR-related orphan receptor B antibody, RAR-related orphan receptor beta antibody, RORB antibody, Rorb antibody, rorb antibody
- 背景
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Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5\'-AGGTCA-3\' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity).
Aliases: bA133M9.1 antibody, NR1F2 antibody, Nuclear receptor ROR-beta antibody, Nuclear receptor RZR beta antibody, Nuclear receptor RZR-beta antibody, Nuclear receptor subfamily 1 group F member 2 antibody, OTTHUMP00000021486 antibody, RAR related orphan receptor B antibody, RAR related orphan receptor beta antibody, Retinoic acid binding receptor beta antibody, Retinoid-related orphan receptor-beta antibody, ROR BETA antibody, Rorb antibody, RORB_HUMAN antibody, RZR BETA antibody, RZRB antibody
- UniProt
- Q92753
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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